Zdhhc1 - zinc finger, DHHC domain containing 1 Gene

Also Known as DHHC-1; 4432412D04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70796

Summary

Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including Antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of defense response to virus by host. Acts upstream of or within protein palmitoylation. Located in endosome membrane. Is expressed in several structures, including adrenal gland; brain; genitourinary system; heart; and lung. Orthologous to human ZDHHC1 (zinc finger DHHC-type containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Zdhhc1 Products (8)

mRNA Protein Name
NM_001357252.2 NP_001344181.1 palmitoyltransferase ZDHHC1 isoform 2
NM_001379006.1 NP_001365935.1 palmitoyltransferase ZDHHC1 isoform 1
NM_001379007.1 NP_001365936.1 palmitoyltransferase ZDHHC1 isoform 1
NM_001379008.1 NP_001365937.1 palmitoyltransferase ZDHHC1 isoform 2
NM_001379009.1 NP_001365938.1 palmitoyltransferase ZDHHC1 isoform 3
NM_001379010.1 NP_001365939.1 palmitoyltransferase ZDHHC1 isoform 3
NM_001379011.1 NP_001365940.1 palmitoyltransferase ZDHHC1 isoform 3
NM_175160.5 NP_780369.1 palmitoyltransferase ZDHHC1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables palmitoyltransferase activity IDA
IDA: Inferred from direct assay
15603741 MGI
enables protein-cysteine S-palmitoyltransferase activity IDA
IDA: Inferred from direct assay
23687301 MGI
Biological Process GO Annotation Evidence References Source
involved in antiviral innate immune response IMP
IMP: Inferred from mutant phenotype
25299331 MGI
involved in peptidyl-L-cysteine S-palmitoylation IDA
IDA: Inferred from direct assay
23687301 MGI
involved in positive regulation of defense response to virus by host IMP
IMP: Inferred from mutant phenotype
25299331 MGI
involved in positive regulation of protein localization to endosome IMP
IMP: Inferred from mutant phenotype
23687301 MGI
involved in positive regulation of protein oligomerization IMP
IMP: Inferred from mutant phenotype
25299331 MGI
acts upstream of or within protein palmitoylation IDA
IDA: Inferred from direct assay
15603741 MGI
Cellular Component GO Annotation Evidence References Source
located in endosome membrane IDA
IDA: Inferred from direct assay
23687301 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

palmitoyltransferase ZDHHC1

  • probable palmitoyltransferase ZDHHC1

  • zinc finger DHHC domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16011 ZDHHC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zdhhc1 NCBI NCBI:29800