ALK5-IN-33
ALK5-IN-33 (Compound EX-10) is a selective, orally active ALK-5 inhibitor with an IC50 ≤10 nM.
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- CAS No.: 2785430-89-7
- Formule: C23H23N7O
- Masse moléculaire:413.48
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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ALK5 ≤10 nM (IC50) |
ALK2 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female athymic nude mice, A549 xenograft model[1]
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Dosage:10, 50, 75 and 100 mg/kg
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Administration:Oral gavage, once
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Result:Reduced the phospho SMAD2 levels (p-SMAD2) in a dose dependent fashion.
Chemical Information
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CAS No. 2785430-89-7
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Masse moléculaire 413.48
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Formule C23H23N7O
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SMILES
CC1=CC=CC2=C(NC3=NC(NC4=CC=C(N5CCOCC5)C=C4)=NC=C3)C=NN=C12
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ALK5-IN-33 Related Classifications
HY-151283 Related Classifications
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