EZH2-IN-16
EZH2-IN-16 (Compound 24) is an inhibitor for histone methyltransferase (EZH2). EZH2-IN-16 inhibits EZH2 and EZH2 Y641F, with IC50 of 37.6 and 79.1 nM. EZH2-IN-16 inhibits proliferation of WSU-DLCL2, with GI50 of 0.2 μM.
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- CAS No.: 2238820-26-1
- Formule: C32H38N4O4
- Masse moléculaire:542.67
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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EZH2 WT 37.6 nM (IC50) |
EZH2 Y641F mutant type 79.1 nM (IC50) |
Chemical Information
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CAS No. 2238820-26-1
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Masse moléculaire 542.67
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Formule C32H38N4O4
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SMILES
O=C(C1=CC(C2=CC=C(N3CCOCC3)C=C2)=CC(N(CC)C(C4CC4)=O)=C1C)NCC5=C(C)C=C(C)NC5=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EZH2-IN-16 Related Classifications
HY-149463 Related Classifications
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