Traf5 - TNF receptor-associated factor 5 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22033

Summary

Predicted to enable enzyme binding activity; identical protein binding activity; and tumor necrosis factor receptor binding activity. Involved in interleukin-17-mediated signaling pathway and regulation of gene expression. Acts upstream of or within positive regulation of cell population proliferation and signal transduction. Located in cytoplasmic side of plasma membrane. Part of CD40 receptor complex. Is expressed in genitourinary system and tongue muscle. Orthologous to human TRAF5 (TNF Receptor associated factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Traf5 Products (1)

mRNA Protein Name
NM_011633.2 NP_035763.2 TNF receptor-associated factor 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
21822257 MGI
Biological Process GO Annotation Evidence Références Source
involved in interleukin-17-mediated signaling pathway IDA
IDA: Inferred from direct assay
21822258 MGI
involved in interleukin-17-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
21822258 MGI
involved in mRNA stabilization IMP
IMP: Inferred from mutant phenotype
21822258 MGI
involved in positive regulation of NF-kappaB transcription factor activity IMP
IMP: Inferred from mutant phenotype
15121867 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
10449775 MGI
acts upstream of or within signal transduction IMP
IMP: Inferred from mutant phenotype
10449775 MGI
involved in signal transduction involved in regulation of gene expression IDA
IDA: Inferred from direct assay
21822258 MGI
involved in signal transduction involved in regulation of gene expression IMP
IMP: Inferred from mutant phenotype
21822258 MGI
Cellular Component GO Annotation Evidence Références Source
part of CD40 receptor complex IDA
IDA: Inferred from direct assay
20614026 MGI
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
20614026 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TNF receptor-associated factor 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS14974 TRAF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174514 Human TNFRSF4 mRNA / Unkown
HY-RS22873 Traf5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29387 Traf5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Traf5 NCBI NCBI:7188