(S)-Thalidomide-5-OH
(S)-Thalidomide-5-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. (S)-Thalidomide-5-OH can be linked to a target protein ligand via a linker to form a PROTAC.
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- CAS No.: 172333-29-8
- Formule: C13H10N2O5
- Masse moléculaire:274.23
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 172333-29-8
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Masse moléculaire 274.23
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Formule C13H10N2O5
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SMILES
O=C1N(C(=O)C=2C1=CC(O)=CC2)[C@@H]3C(=O)NC(=O)CC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S)-Thalidomide-5-OH Related Classifications
HY-W457158 Related Classifications
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