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Cat. No.: HY-105034

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Tiospirone

(Synonyms: BMY 13859-1 free base)

Tiospirone is a 5-HT₂ receptor antagonist with affinity for D₂, 5-HT_1a, and 5-HT₇, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm.

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CAS No.: 87691-91-6
Formule: C₂₄H₃₂N₄O₂S
Masse moléculaire:440.60

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Tiospirone Chemical Structure

CAS No.: 87691-91-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- IC₅₀ & Target
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Description

IC₅₀ & Target

5-HT_1A Receptor

5-HT₇ Receptor

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Chemical Information

CAS No. 87691-91-6
Appearance Solid
Masse moléculaire 440.60
Formule C₂₄H₃₂N₄O₂S
Color White to off-white
SMILES

O=C1N(CCCCN2CCN(CC2)C3=NSC4=C3C=CC=C4)C(CC5(CCCC5)C1)=O
Synonyms

BMY 13859-1 free base
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Arolfo MP, et, al. Effects of amperozide and tiospirone, atypical antipsychotic 5-HT2 drugs, on food-reinforced behavior in rats. Physiol Behav. 1999 Dec;68(1-2):93-8. [Content Brief]

[2]. Arolfo MP, et, al. Tiospirone and the reinforcing effects of cocaine in the conditioned place preference paradigm in rats. J Pharm Pharmacol. 2000 Aug;52(8):977-81. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Tiospirone

Voir tous les produits spécifiques à Isoform 5-HT Receptor

Activité biologique

Chemical Information

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Calculators

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Tiospirone Related Classifications

HY-105034 Related Classifications