1227413-92-4
1227413-92-4
Chemical Structure
FABP4/5-IN-7
- CAS No.: 1227413-92-4
- Formula:C19H15ClN4O2
- Molecular Weight:366.80
InChIKey: DHVPJCVPOZYDTH-UHFFFAOYSA-N
SMILES: O=C1C=C(COC2=C(C)C(Cl)=CC=C2)N=C3NC(C4=CC=CC=C4)=NN13
Biological Activity: FABP4/5-IN-7 is a dual FABP4/FABP5 inhibitor, with an IC50 of 0.8 μM and a Kd of 0.01 μM for FABP4, and an IC50 of 1.4 μM for FABP5. FABP4/5-IN-7 inhibits lipolysis in adipocytes. FABP4/5-IN-7 inhibits MCP-1 release in macrophages. FABP4/5-IN-7 improves dyslipidemia in diet-induced obese mice. FABP4/5-IN-7 can be used in studies related to dyslipidemia[1].
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FABP4/5-IN-7 | FABP4/5-IN-7 is a dual FABP4/FABP5 inhibitor, with an IC50 of 0.8 μM and a Kd of 0.01 μM for FABP4, and an IC50 of 1.4 μM for FABP5. FABP4/5-IN-7 inhibits lipolysis in adipocytes. FABP4/5-IN-7 inhibits MCP-1 release in macrophages. FABP4/5-IN-7 improves dyslipidemia in diet-induced obese mice. FABP4/5-IN-7 can be used in studies related to dyslipidemia. | |||||||||||||||||||||
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References
Keywords
