2573304-30-8
Chemical Structure
KTX-582 intermediate-3
- CAS No.: 2573304-30-8
- Formula:C26H29F3N4O4
- Molecular Weight:518.53
IUPAC Name: ethyl (1r,4r)-4-(6-(2-hydroxypropan-2-yl)-5-(6-(trifluoromethyl)picolinamido)-1H-indazol-1-yl)cyclohexane-1-carboxylate
InChIKey: XQXMEFBBKXADRJ-JCNLHEQBSA-N
SMILES: CC(O)(C1=C(NC(C2=CC=CC(C(F)(F)F)=N2)=O)C=C3C=NN([C@@H]4CC[C@H](CC4)C(OCC)=O)C3=C1)C
Biological Activity: KTX-582 intermediate-3 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].
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KTX-582 intermediate-3 | KTX-582 intermediate-3 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively. | |||||||||||||||||||||
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