2758904-45-7
2758904-45-7
Chemical Structure
EGFR-IN-104
- CAS No.: 2758904-45-7
- Formula:C23H27N7OS
- Molecular Weight:449.57
InChIKey: SSAIZFOIMGGUDG-UHFFFAOYSA-N
SMILES: OC1=CC=CC=C1C2=NC(CCSC3)=C3C(NCC4=CN=C(N5CCN(C)CC5)N=C4)=N2
Biological Activity: EGFR-IN-104 (Compound A23) is an effective inhibitor of EGFR, with IC50 values of 0.33 μM and 0.133 μM against EGFRL858R/T790M and EGFRDel19/T790M/C797S, respectively. EGFR-IN-104 exhibits anticancer activity both in vitro and in vivo[1].
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EGFR-IN-104 | EGFR-IN-104 (Compound A23) is an effective inhibitor of EGFR, with IC50 values of 0.33 μM and 0.133 μM against EGFRL858R/T790M and EGFRDel19/T790M/C797S, respectively. EGFR-IN-104 exhibits anticancer activity both in vitro and in vivo. | |||||||||||||||||||||
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References
Keywords
