EGFR-IN-104
EGFR-IN-104 (Compound A23) is an effective inhibitor of EGFR, with IC50 values of 0.33 μM and 0.133 μM against EGFRL858R/T790M and EGFRDel19/T790M/C797S, respectively. EGFR-IN-104 exhibits anticancer activity both in vitro and in vivo.
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- CAS. Nr.: 2758904-45-7
- Formel: C23H27N7OS
- Molecular Weight:449.57
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Alle EGFR Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
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EGFRL858R/T790M 0.33 μM (IC50) |
EGFRL858R/T790M/C797S 0.133 μM (IC50) |
Chemical Information
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CAS. Nr. 2758904-45-7
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Molecular Weight 449.57
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Formel C23H27N7OS
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SMILES
OC1=CC=CC=C1C2=NC(CCSC3)=C3C(NCC4=CN=C(N5CCN(C)CC5)N=C4)=N2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
EGFR-IN-104 Related Classifications
HY-161319 Related Classifications
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