510721-85-4
510721-85-4
Chemical Structure
AR03
Synonym(s): BMH-23
- CAS No.: 510721-85-4
- Formula:C15H15N3
- Molecular Weight:237.30
IUPAC Name: 2,4,9-trimethylbenzo[b][1,8]naphthyridin-5-amine
InChIKey: WRUVTYDQVPMYDZ-UHFFFAOYSA-N
SMILES: CC1=C2N=C3N=C(C=C(C3=C(C2=CC=C1)N)C)C
Biological Activity: AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC50 of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AR03 | 99.1% | AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC50 of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells. | ||||||||||||||||||||
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References
Keywords
