569-64-2
Chemical Structure
Basic green 4
Synonym(s): Malachite green
- CAS No.: 569-64-2
- Formula:C23H25ClN2
- Molecular Weight:364.91
IUPAC Name: N-(4-((4-(dimethylamino)phenyl)(phenyl)methylene)cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium chloride
InChIKey: FDZZZRQASAIRJF-UHFFFAOYSA-M
SMILES: C/[N+](C)=C1C=C/C(C=C/1)=C(C2=CC=C(N(C)C)C=C2)\C3=CC=CC=C3.[Cl-]
Biological Activity: Basic green 4 (Malachite green) is a cationic dye that is widely used as a bactericide in aquaculture and is also commonly used in laboratories for the determination of phosphates. Basic green 4 exhibits high cytotoxicity and carcinogenicity to mammalian cells, specifically shown by its IC50 values of 2.03 µM for HEp-2 human laryngeal cells and 13.8 µM for Caco-2 human colorectal adenocarcinoma cells, and it can promote the development of liver tumors. The maximum absorbance wavelength is 621 nm[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Basic green 4 | 95.88% | Basic green 4 (Malachite green) is a cationic dye that is widely used as a bactericide in aquaculture and is also commonly used in laboratories for the determination of phosphates. Basic green 4 exhibits high cytotoxicity and carcinogenicity to mammalian cells, specifically shown by its IC50 values of 2.03 µM for HEp-2 human laryngeal cells and 13.8 µM for Caco-2 human colorectal adenocarcinoma cells, and it can promote the development of liver tumors. The maximum absorbance wavelength is 621 nm. | ||||||||||||||||||||
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References
- [1]. A A Baykov, et al. A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay. Anal Biochem. 1988 Jun;171(2):266-70. [Content Brief]
- [2]. Lloyd D. Wright, et al. Effect of Malachite Green and Formalin on the Survival of Largemouth Bass Eggs and Fry. The Progressive Fish-Culturist. 2011 Jan; Pages 155-157.
- [3]. Chowdhury. S, et al. Sea shell powder as a new adsorbent to remove Basic Green 4 (Malachite Green) from aqueous solutions: Equilibrium, kinetic and thermodynamic studies. Chemical Engineering Journal, 164(1), 168–177.
