60-56-0
60-56-0
Chemical Structure
Methimazole
Synonym(s): Thiamazole
- CAS No.: 60-56-0
- Formula:C4H6N2S
- Molecular Weight:114.17
IUPAC Name: 1-methyl-1H-imidazole-2-thiol
InChIKey: PMRYVIKBURPHAH-UHFFFAOYSA-N
SMILES: SC1=NC=CN1C
Biological Activity: Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity[1][2][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Methimazole | 99.97% | Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Methimazole (Standard) | 99.14% | Methimazole (Standard) (Thiamazole (Standard)) is the analytical standard of Methimazole (HY-B0208) . This product is intended for research and analytical applications. Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Methimazole-d3 | 99.65% | Methimazole-d3 is a deuterium labeled Methimazole (HY-B0208). Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.72
HY-W0159471,2-Dimethylimidazole -
Similarity Score 0.70
HY-Y1359R2-Methylimidazole (Standard) -
Similarity Score 0.69
HY-N8848R1-Methyl-2-(methylthio)-1H-imidazole (Standard) -
Similarity Score 0.68
HY-591371-Methylimidazole -
Similarity Score 0.67
HY-1340627-Methyl-6-mercaptopurine -
Similarity Score 0.67
HY-W0622162-Aminoimidazole -
Similarity Score 0.67
HY-W1244211,4-Dihydropyrazine-2,3-dithione -
Similarity Score 0.66
HY-B0503S2-Thiouracil-13C,15N2 -
Explore the MedChemAI to find more analogs
References
- [1]. Tatara MR, et al. Effects of long-term oral administration of methimazole on femur and tibia properties in male Wistar rats. Biomed Pharmacother. 2017 Oct;94:124-128. [Content Brief]
- [2]. Reza Heidari, et al. Mechanisms of methimazole cytotoxicity in isolated rat hepatocytes. Drug Chem Toxicol. 2013 Oct;36(4):403-11. [Content Brief]
- [4]. Heidari R, et, al. Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole-Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine. Adv Pharm Bull. 2014;4(1):21-8. [Content Brief]
