60-56-0
60-56-0
Chemical Structure
Methimazole
Synonym(s): Thiamazole
- CAS No.: 60-56-0
- Formula:C4H6N2S
- Molecular Weight:114.17
IUPAC Name: 1-methyl-1H-imidazole-2-thiol
InChIKey: PMRYVIKBURPHAH-UHFFFAOYSA-N
SMILES: S=C1NC=CN1C
Biological Activity: Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity[1][2][4].
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Methimazole | 99.97% | Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity. | ||||||||||||||||||||
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Methimazole (Standard) | ≥98% | Methimazole (Standard) (Thiamazole (Standard)) is the analytical standard of Methimazole (HY-B0208) . This product is intended for research and analytical applications. Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity. | ||||||||||||||||||||
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Methimazole-d3 | 99.00% | Methimazole-d3 is a deuterium labeled Methimazole (HY-B0208). Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity. | ||||||||||||||||||||
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References
- [1]. Tatara MR, et al. Effects of long-term oral administration of methimazole on femur and tibia properties in male Wistar rats. Biomed Pharmacother. 2017 Oct;94:124-128. [Content Brief]
- [2]. Reza Heidari, et al. Mechanisms of methimazole cytotoxicity in isolated rat hepatocytes. Drug Chem Toxicol. 2013 Oct;36(4):403-11. [Content Brief]
- [4]. Heidari R, et, al. Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole-Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine. Adv Pharm Bull. 2014;4(1):21-8. [Content Brief]
