Methimazole-d3
Based on 1 Customer Validation
Methimazole-d3 is a deuterium labeled Methimazole (HY-B0208). Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity.
For research use only. We do not sell to patients.
- Purity: 99.00%
- CAS No.: 1160932-07-9
- Formula: C4H3D3N2S
- Molecular Weight:117.19
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1160932-07-9
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Unlabeled Cas 60-56-0
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Appearance Solid
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Molecular Weight 117.19
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Formula C4H3D3N2S
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Color White to off-white
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SMILES
S=C1NC=CN1C([2H])([2H])[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (853.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 50 mg/mL (426.66 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 8.5332 mL | 42.6658 mL | 85.3315 mL | 213.3288 mL |
| 5 mM | 1.7066 mL | 8.5332 mL | 17.0663 mL | 42.6658 mL | |
| 10 mM | 0.8533 mL | 4.2666 mL | 8.5332 mL | 21.3329 mL | |
| 15 mM | 0.5689 mL | 2.8444 mL | 5.6888 mL | 14.2219 mL | |
| 20 mM | 0.4267 mL | 2.1333 mL | 4.2666 mL | 10.6664 mL | |
| 25 mM | 0.3413 mL | 1.7066 mL | 3.4133 mL | 8.5332 mL | |
| 30 mM | 0.2844 mL | 1.4222 mL | 2.8444 mL | 7.1110 mL | |
| 40 mM | 0.2133 mL | 1.0666 mL | 2.1333 mL | 5.3332 mL | |
| 50 mM | 0.1707 mL | 0.8533 mL | 1.7066 mL | 4.2666 mL | |
| 60 mM | 0.1422 mL | 0.7111 mL | 1.4222 mL | 3.5555 mL | |
| 80 mM | 0.1067 mL | 0.5333 mL | 1.0666 mL | 2.6666 mL | |
| 100 mM | 0.0853 mL | 0.4267 mL | 0.8533 mL | 2.1333 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Methimazole-d3 Related Classifications
HY-B0208S Related Classifications
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