69770-45-2
Chemical Structure
Flumethrin
Synonym(s): FCR 2769
- CAS No.: 69770-45-2
- Formula:C28H22Cl2FNO3
- Molecular Weight:510.38
IUPAC Name: cyano(4-fluoro-3-phenoxyphenyl)methyl (Z)-3-(2-chloro-2-(4-chlorophenyl)vinyl)-2,2-dimethylcyclopropane-1-carboxylate
InChIKey: YXWCBRDRVXHABN-JCMHNJIXSA-N
SMILES: N#CC(C1=CC=C(C(OC2=CC=CC=C2)=C1)F)OC(C3C(C3(C)C)/C=C(C4=CC=C(C=C4)Cl)\Cl)=O
Biological Activity: Flumethrin (FCR 2769) is a pyrethroid insecticide and acaricide. Flumethrin targets voltage-gated sodium channels and estrogen receptor α (ERα). Flumethrin induces cytotoxicity, apoptosis, genotoxicity and DNA damage in breast cancer cells by regulating the expression of BCL2, BAX, TP53 and P21 genes. Flumethrin is applicable to relevant studies on ectoparasite infections (tick and flea burdens) in dogs and cats, as well as breast cancer[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Flumethrin | 99.29% | Flumethrin (FCR 2769) is a pyrethroid insecticide and acaricide. Flumethrin targets voltage-gated sodium channels and estrogen receptor α (ERα). Flumethrin induces cytotoxicity, apoptosis, genotoxicity and DNA damage in breast cancer cells by regulating the expression of BCL2, BAX, TP53 and P21 genes. Flumethrin is applicable to relevant studies on ectoparasite infections (tick and flea burdens) in dogs and cats, as well as breast cancer. | ||||||||||||||||||||
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Flumethrin (Standard) | ≥98% | Flumethrin (Standard) (FCR 2769 (Standard)) is the analytical standard of Flumethrin (HY-107835). This product is intended for research and analytical applications. Flumethrin (FCR 2769) is a pyrethroid insecticide and acaricide. Flumethrin targets voltage-gated sodium channels and estrogen receptor α (ERα). Flumethrin induces cytotoxicity, apoptosis, genotoxicity and DNA damage in breast cancer cells by regulating the expression of BCL2, BAX, TP53 and P21 genes. Flumethrin is applicable to relevant studies on ectoparasite infections (tick and flea burdens) in dogs and cats, as well as breast cancer. | ||||||||||||||||||||
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Flumethrin-d5 | Flumethrin-d5 (FCR 2769-d5) is the deuterium labeled Flumethrin (HY-107835). Flumethrin (FCR 2769) is a pyrethroid insecticide and acaricide. Flumethrin targets voltage-gated sodium channels and estrogen receptor α (ERα). Flumethrin induces cytotoxicity, apoptosis, genotoxicity and DNA damage in breast cancer cells by regulating the expression of BCL2, BAX, TP53 and P21 genes. Flumethrin is applicable to relevant studies on ectoparasite infections (tick and flea burdens) in dogs and cats, as well as breast cancer. | |||||||||||||||||||||
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- [1]. Stanneck D, et al. The synergistic action of imidacloprid and flumethrin and their release kinetics from collars applied for ectoparasite control in dogs and cats. Parasit Vectors. 2012;5:73. Published 2012 Apr 12. [Content Brief]
- [2]. Kara-Ertekin S, et al. In vitro toxicological assessment of flumethrin's effects on MCF-7 breast cancer cells. Hum Exp Toxicol. 2021;40(12):2165-2177. [Content Brief]
- [3]. Qi S, et al. Flumethrin at sublethal concentrations induces stresses in adult honey bees (Apis mellifera L.). Sci Total Environ. 2020;700:134500. [Content Brief]
- [4]. Başçi Z, et al. Toxicokinetic of flumethrin in rabbits. Drug Chem Toxicol. 2015;38(1):92-97. [Content Brief]
