97-18-7
97-18-7
Chemical Structure
Bithionol
- CAS No.: 97-18-7
- Formula:C12H6Cl4O2S
- Molecular Weight:356.05
IUPAC Name: 6,6'-thiobis(2,4-dichlorophenol)
InChIKey: JFIOVJDNOJYLKP-UHFFFAOYSA-N
SMILES: OC1=C(Cl)C=C(Cl)C=C1SC2=CC(Cl)=CC(Cl)=C2O
Biological Activity: Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC50: 4 μM)[1][2].
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Bithionol | 99.32% | Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC50: 4 μM). | ||||||||||||||||||||
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Bithionol (Standard) | ≥98% | Bithionol (Standard) is the analytical standard of Bithionol. This product is intended for research and analytical applications. Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC50: 4 μM). | ||||||||||||||||||||
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References
- [1]. Florent RL, et al. In vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD). Dis Aquat Organ. 2010 Sep 17;91(3):257-62. [Content Brief]
- [2]. Silke Kleinboelting, et al. Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site. J Biol Chem. 2016 Apr 29;291(18):9776-84. [Content Brief]
Keywords
