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Art. -Nr.: HY-N19754

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Cladospirone B

Cladospirone B is a secondary metabolite of the endophytic fungus Lasiodiplodia theobromae. Cladospirone B exhibits trypanocidal activity, with a MIC of 17.8 µM against Trypanosoma brucei. Cladospirone B can be used in the research of African human trypanosomiasis (sleeping sickness).

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CAS. Nr.: 307503-97-5
Formel: C₂₀H₁₄O₆
Molecular Weight:350.32

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cladospirone B Chemical Structure

CAS. Nr.: 307503-97-5

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Biologische Aktivität
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- Cellular Effect
- In Vitro
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Biologische Aktivität

Beschreibung

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Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	10 μM Compound: 18	Cytotoxicity against human A2780 cells by MTT assay Cytotoxicity against human A2780 cells by MTT assay	[PMID: 25237727]

In Vitro

Cladospirone B shows no activity against bacteria and fungi^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 307503-97-5
Molecular Weight 350.32
Formel C₂₀H₁₄O₆
SMILES

O[C@H]1C2(OC3=CC=CC4=C3C(O2)=CC=C4)C5=C(O)C=CC(O)=C5C(C1)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Berkleasmium sp.
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Kamal N, et al. Metabolomics-Guided Isolation of Anti-trypanosomal Metabolites from the Endophytic Fungus Lasiodiplodia theobromae. Planta Med. 2017;83(6):565-573. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Cladospirone B

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Cladospirone B Related Classifications

HY-N19754 Related Classifications