Nr6a1 - nuclear receptor subfamily 6, group A, member 1 Gene

Also Known as RTR; Gcnf; NCNF; 1700113M01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14536

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within gamete generation and negative regulation of transcription by RNA polymerase II. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; embryo ectoderm; genitourinary system; nervous system; and retina. Orthologous to human NR6A1 (nuclear receptor subfamily 6 group A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Nr6a1 Products (3)

mRNA Protein Name
NM_001159548.1 NP_001153020.1 nuclear receptor subfamily 6 group A member 1 isoform 2
NM_001159549.1 NP_001153021.1 nuclear receptor subfamily 6 group A member 1 isoform 3
NM_010264.4 NP_034394.1 nuclear receptor subfamily 6 group A member 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
9099702 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
9099702 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11702949 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
9099702 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11702949 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
7854358 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
7854358 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in gamete generation IEP
IEP: Inferred from expression pattern
7835709 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11702949 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
12381721 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9099702 MGI
Cellular Component GO Annotation Evidence Verweise Source
part of transcription regulator complex IDA
IDA: Inferred from direct assay
16166633 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear receptor subfamily 6 group A member 1

  • germ cell nuclear factor

  • mGCNF

  • retinoid receptor-related testis-specific receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS09555 NR6A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22688 Nr6a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29202 Nr6a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr6a1 NCBI NCBI:2649