Srsf3 - serine and arginine-rich splicing factor 3 Gene

Also Known as X16; Sfrs3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20383

Summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding Other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the Other not protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010]

Srsf3 Products (1)

mRNA Protein Name
NM_013663.5 NP_038691.1 serine/arginine-rich splicing factor 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables phospholipase binding IPI
IPI: Inferred from physical interaction
17022104 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
29799838 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in nuclear speck IDA
IDA: Inferred from direct assay
17022104 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/arginine-rich splicing factor 3

  • pre-mRNA-splicing factor SRP20

  • splicing factor, arginine/serine-rich 3 (SRp20)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-148660 SFI003 Inducer 99.75% Unkown
HY-125201 Indazole 1 Inhibitor / Unkown
HY-RS13794 SRSF3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18844 Srsf3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25336 Srsf3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srsf3 NCBI NCBI:6428