Hmgn3 - high mobility group nucleosomal binding domain 3 Gene

Also Known as TRIP7; 1110002A15Rik; 6330514M13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94353

Summary

Enables chromatin binding activity. Acts upstream of or within positive regulation of DNA-binding transcription factor activity; positive regulation of transcription by RNA polymerase II; and regulation of Insulin secretion involved in cellular response to glucose stimulus. Located in nucleus. Is expressed in several structures, including brain; epithelium; eye; genitourinary system; and limb. Orthologous to human HMGN3 (high mobility group nucleosomal binding domain 3). [provided by Alliance of Genome Resources, Apr 2022]

Hmgn3 Products (2)

mRNA Protein Name
NM_026122.4 NP_080398.1 high mobility group nucleosome-binding domain-containing protein 3 isoform Hmgn3a
NM_175074.2 NP_778249.1 high mobility group nucleosome-binding domain-containing protein 3 isoform Hmgn3b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables chromatin binding IDA
IDA: Inferred from direct assay
11356838 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within positive regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
19651901 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
19651901 MGI
acts upstream of or within regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
19651901 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21278158 MGI
acts upstream of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
19651901 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in nucleus IDA
IDA: Inferred from direct assay
15082770 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

high mobility group nucleosome-binding domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS06245 HMGN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19205 Hmgn3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25693 Hmgn3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hmgn3 NCBI NCBI:9324