HDAC6-IN-47
HDAC6-IN-47 (Compound S-29b) is inhibitor for HDAC, which exhibits high affinities to HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, HDAC10 with Ki of 60, 56, 162, 0.44, 362 and 849 nM, respectively. HDAC6-IN-47 causes tubulin hyperacetylation in MV4-11, inhibits the proliferation of MV4-11 with an EC50 of 0.50 µM. HDAC6-IN-47 can be used in research of leukemia.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C29H33N5O6
- Molecular Weight:547.60
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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HDAC6 0.44 nM (Ki) |
HDAC2 56 nM (Ki) |
HDAC1 60 nM (Ki) |
HDAC3 162 nM (Ki) |
HDAC8 362 nM (Ki) |
HDAC10 849 nM (Ki) |
Chemical Information
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Molecular Weight 547.60
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Formel C29H33N5O6
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SMILES
O=C(C1=CC=C(C=C1)CN2C(CN3C(N4C)=O)=C(C5=C2C=CC(OCCN6CCOCC6)=C5)[C@@](C)(C3)C4=O)NO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HDAC6-IN-47 Related Classifications
HY-163834 Related Classifications
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