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Art. -Nr.: HY-N12150

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Isozedoarondiol

Isozedoarondiol can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb. Isozedoarondiol inhibits MMP-1 expression in UVB-treated human keratinocytes.

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CAS. Nr.: 108887-68-9
Formel: C₁₅H₂₄O₃
Molecular Weight:252.35

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Isozedoarondiol Chemical Structure

CAS. Nr.: 108887-68-9

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
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Calculators
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Biologische Aktivität

Beschreibung

Isozedoarondiol can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb. Isozedoarondiol inhibits MMP-1 expression in UVB-treated human keratinocytes^[1].

Alle MMP Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
KB	IC₅₀	>50 μg/mL Compound: 4	Cytotoxicity against human KB cells assessed as reduction in cell viability Cytotoxicity against human KB cells assessed as reduction in cell viability	[PMID: 29274817]
KG-1a	IC₅₀	>100 μg/mL Compound: 4	Cytotoxicity against human KG1a cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human KG1a cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29274817]
MCF7	IC₅₀	>50 μg/mL Compound: 4	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability Cytotoxicity against human MCF7 cells assessed as reduction in cell viability	[PMID: 29274817]
NCI-H187	IC₅₀	>50 μg/mL Compound: 4	Cytotoxicity against human NCI-H187 cells assessed as reduction in cell viability Cytotoxicity against human NCI-H187 cells assessed as reduction in cell viability	[PMID: 29274817]
RAW264.7	IC₅₀	54.2 μM Compound: 19	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay	[PMID: 23755850]

Chemical Information

CAS. Nr. 108887-68-9
Molecular Weight 252.35
Formel C₁₅H₂₄O₃
SMILES

C[C@]1([C@]2([H])[C@](CC1)([H])[C@](O)(CC(/C(C2)=C(C)/C)=O)C)O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Park J-H, Mohamed MAA, Thi NN, et al. Guaiane Sesquiterpenes from the Rhizome of Curcuma xanthorrhiza and Their Inhibitory Effects on UVB-induced MMP-1 Expression in Human Keratinocytes. Natural Product Communications. 2017;12(10).

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biologische Aktivität
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Isozedoarondiol

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Alle MMP Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Isozedoarondiol Related Classifications

HY-N12150 Related Classifications