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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2732 Results for "
intermediate
" in MedChemExpress (MCE) Product Catalog:
Products (2732)
2732 Results for "intermediate" in MCE Product Catalog:
32
32 Publications Verification
Synonyms: β-Nicotinamide mononucleotide; β-NM; NMN
Category:
Neurological Disease Other disease Anti-aging Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Disease Research Fields Cancer
Target:
30
30 Cited Publications
Target:
Forschungsgebiete:
TRAM-34 is a highly selective blocker of intermediate-conductance calcium-activated K + channel (IKCa1) (Kd=20 nM).
25
22
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
Target:
22
Target:
Forschungsgebiete:
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
20
Category:
Human Gut Microbiota Metabolites Microorganisms Disease markers Metabolic Disease Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
17
11
11 Cited Publications
Forschungsgebiete:
IMT1 is a first-in-class specific and noncompetitive human mitochondrial RNA polymerase (POLRMT) inhibitor. IMT1 causes a conformational change of POLRMT, which blocks substrate binding and transcription in a dose-dependent way in vitro. IMT1 reduces deoxynucleoside triphosphate levels and citric acid cycle intermediates, resulting in a marked depletion of cellular amino acid levels. IMT1 has the potential for mitochondrial transcription disorders related diseases .
11
11
11 Cited Publications
Art. -Nr.: HY-W015410
CAS. Nr.: 150-90-3
Target:
9
9 Cited Publications
Synonyms: 6PPD-Quinone
Category:
Alkaloids Quinones Other Alkaloids Other Diseases Benzene Quinones Endogenous metabolite Disease Research Fields
Target:
8
8 Cited Publications
Art. -Nr.: HY-W017389
CAS. Nr.: 69-89-6
8
8 Cited Publications
Art. -Nr.: HY-N3007
CAS. Nr.: 73692-50-9
Category:
Plants Endogenous metabolite Human Gut Microbiota Metabolites other families Flavonoids Chalcones Phenols Polyphenols Disease Research Fields Inflammation/Immunology
Target:
7
7 Cited Publications
Art. -Nr.: HY-W010347
CAS. Nr.: 6027-13-0
Category:
Human Gut Microbiota Metabolites Microorganisms Anti-aging Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
7
7 Cited Publications
Synonyms: DDD00107587
Target:
Forschungsgebiete:
Madrasin (DDD00107587) is a splicing inhibitor that prevents formation of both splicing intermediates and products in vitro and interferes with one or more early steps in the pathway of spliceosome assembly. Madrasin also can inhibit pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA in cells .
7
7 Cited Publications
Synonyms: Acetyl-CoA trisodium
7
7 Cited Publications
Synonyms: Acetyl-CoA lithium
7
6
6 Cited Publications
Art. -Nr.: HY-W013636
CAS. Nr.: 328-50-7
Synonyms: Alpha-Ketoglutaric acid; 2-Oxoglutaric acid
Category:
Anti-aging Endocrine diseases Endogenous metabolite Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Other Diseases Disease markers Nervous System Disorder Disease Research Fields
Target:
6
6 Cited Publications
Art. -Nr.: HY-W013636A
CAS. Nr.: 22202-68-2
Synonyms: Alpha-Ketoglutaric acid Sodium
Target:
-
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
