SIRT2-IN-13
SIRT2-IN-13 (compound 7c) is an inhibitor of SIRT2 and induces apoptosis. SIRT2-IN-13 selectively inhibits colon cancer and leukemia cells and arrests the cell cycle in the G2 phase.
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- Formel: C31H31N3S
- Molecular Weight:477.66
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
SIRT2[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Panel NCI-60 (60 carcinoma cell lines) | GI50 |
0.22 μM
Compound: 7b
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Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) cells incubated for 48 hrs by SRB assay
Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) cells incubated for 48 hrs by SRB assay
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[PMID: 38484678] |
Chemical Information
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Molecular Weight 477.66
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Formel C31H31N3S
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SMILES
CN(C)C1=CC(CNCCSC2(C3=CC=CC=C3)C4=C(C=CC=C4)C=CC5=C2C=CC=C5)=NC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SIRT2-IN-13 Related Classifications
HY-161339 Related Classifications
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