ZW-6-052
ZW-6-052 (compound 20), the derivative of ZW-18-116 (HY-180550), is a dual-target PROTAC degrader for the oncoproteins TRKA and RET. ZW-6-052 induces degradation of TMP3-TRKA in KM12 mouse xenograft models. ZW-6-052 can be used for RET or TRKA-derived cancer research, such as thyroid, lung, and colon cancers.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C46H49N9O9
- Molecular Weight:871.94
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
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Biologische Aktivität
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TrkA |
Chemical Information
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Molecular Weight 871.94
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Formel C46H49N9O9
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SMILES
O=C(NC1=NOC(C(C)(C)C)=C1)CC2=CC=C(N3C=NC4=CC(C5=CN(CCOCCOCCOCCNC6=CC=CC(C(N7C(CC8)C(NC8=O)=O)=O)=C6C7=O)N=C5)=CC=C34)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
ZW-6-052 Related Classifications
HY-180551 Related Classifications
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