Dinotefuran-d3
Based on 1 Customer Validation
Dinotefuran-d3 is the deuterium labeled Dinotefuran. Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.
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- CAS No.: 2934813-27-9
- Formule: C7H11D3N4O3
- Masse moléculaire:205.23
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2934813-27-9
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Unlabeled Cas 165252-70-0
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Appearance Solid
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Masse moléculaire 205.23
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Formule C7H11D3N4O3
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Color White to off-white
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SMILES
[2H]C([2H])([2H])N/C(N[N+]([O-])=O)=N\CC1CCOC1
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Synonyms
MTI-446-d3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
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Fiche technique (273 KB)
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SDS (700 KB)
- English - EN (700 KB)
- Français - FR (700 KB)
- Deutsch - DE (700 KB)
- Norwegian - NO (700 KB)
- Español - ES (700 KB)
- Swedish - SV (700 KB)
- Italian - IT (700 KB)
- Korean - KR (700 KB)
- Portuguese - PT (700 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Liu T, et al. Biochemical and genetic toxicity of dinotefuran on earthworms (Eisenia fetida). Chemosphere. 2017 Jun;176:156-164. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)