Kazusamycin B
Kazusamycin B is an antibiotic that could be isolated from the fermentation broth of Streptomyces sp. No. 81-484. Kazusamycin B inhibits cell growth and arrests cell cycle at G1 phase. Kazusamycin B can be used in research of cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 107140-30-7
- Formule: C32H46O7
- Masse moléculaire:542.70
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Antibiotic
More
Activité biologique
Kazusamycin B (PD 124895; 5 ng/mL; 24 h; 1210 cells) has cell cytotoxicity in a time-dependent manner and arrests cell cycle at G1 phase[2].
Kazusamycin B (5-50 ng/mL; 0-6 h; 1210 cells) B inhibits RNA synthesis moderately but specifically at 2 hours[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:1210 cells
-
Concentration:5 ng/mL
-
Incubation Time:24 h
-
Result:Arrested cell cycle at G1 phase at 4 hours.
Chemical Information
-
CAS No. 107140-30-7
-
Masse moléculaire 542.70
-
Formule C32H46O7
-
SMILES
O=C(/C=C(CC(C(C(C(C(/C=C(/C=C/CC(/C=C(/C=C/C1C(C=CC(O1)=O)C)C)C)C)CO)=O)C)O)C)\C)O
-
Synonyms
PD 124895; CL-1957E
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Funaishi K, et, al. Kazusamycin B, a novel antitumor antibiotic. J Antibiot (Tokyo). 1987 Jun;40(6):778-85. [Content Brief]
[2]. Takamiya K, et, al. The effect of kazusamycin B on the cell cycle and morphology of cultured L1210 cells. J Antibiot (Tokyo). 1988 Dec;41(12):1854-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Kazusamycin B Related Classifications
HY-118331 Related Classifications
Powered by Bioz