Lunarine
Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD50 of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with Ki of 304 μM.
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- CAS No.: 24185-51-1
- Formule: C25H31N3O4
- Masse moléculaire:437.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
Chemical Information
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CAS No. 24185-51-1
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Masse moléculaire 437.53
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Formule C25H31N3O4
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SMILES
O=C1C[C@]2([H])[C@]3(CC1)C4=CC(/C=C/C(NCCCNCCCCNC(/C=C/3)=O)=O)=CC=C4O2
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Hamilton CJ, et al., Time-dependent inhibitors of trypanothione reductase: analogues of the spermidine alkaloid lunarine and related natural products. Bioorg Med Chem. 2006 Apr 1;14(7):2266-78. [Content Brief]
[2]. HENDERSON FG, et al., The pharmacology of lunarine, the alkaloid of Lunaria biennis. J Am Pharm Assoc Am Pharm Assoc. 1950 Sep;39(9):516-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lunarine Related Classifications
HY-129278 Related Classifications
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