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Cat. No.: HY-106964A

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(Rac)-S 16924

(Rac)-S 16924 is a partial agonist of the 5-HT1A receptor. (Rac)-S 16924 regulates signaling through its interaction with the 5-HT1A receptor, and (Rac)-S 16924 can stabilize the receptor in its G-protein-coupled conformation without fully activating it, which may affect intracellular signaling pathways associated with this receptor. (Rac)-S 16924 can be used to study the 5-HT1A receptor in mental disorders, especially schizophrenia.

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CAS No.: 734513-52-1
Formule: C₂₂H₂₄FNO₄
Masse moléculaire:385.43

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

(Rac)-S 16924 Chemical Structure

CAS No.: 734513-52-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- IC₅₀ & Target
Chemical Information
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Activité biologique

Description

IC₅₀ & Target

5-HT_1A Receptor

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Chemical Information

CAS No. 734513-52-1
Masse moléculaire 385.43
Formule C₂₂H₂₄FNO₄
SMILES

FC1=CC=C(C=C1)C(CC2CN(CC2)CCOC3=C4OCCOC4=CC=C3)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Newman-Tancredi A, et al. Efficacy of antipsychotic agents at human 5-HT1A receptors determined by [3H] WAY100, 635 binding affinity ratios: relationship to efficacy for G-protein activation[J]. European journal of pharmacology, 2001, 428(2): 177-184. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(Rac)-S 16924

Voir tous les produits spécifiques à Isoform 5-HT Receptor

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Chemical Information

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Références

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(Rac)-S 16924 Related Classifications

HY-106964A Related Classifications