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Cat. No.: HY-19297

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SB-247853

SB-247853 is a highly specific 5-HT_2c receptor antagonist. SB-247853 induces orthostatic intolerance during head-up tilting. SB-247853 can be used in the research of cardiovascular diseases.

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CAS No.: 200711-10-0
Formule: C₂₂H₁₉F₃N₄O₂
Masse moléculaire:428.41

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

SB-247853 Chemical Structure

CAS No.: 200711-10-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

SB-247853 is a highly specific 5-HT_2c receptor antagonist. SB-247853 induces orthostatic intolerance during head-up tilting. SB-247853 can be used in the research of cardiovascular diseases^[1].

IC₅₀ & Target^[1]

5-HT_2C Receptor

Voir tous les produits spécifiques à Isoform 5-HT Receptor :

Chemical Information

CAS No. 200711-10-0
Masse moléculaire 428.41
Formule C₂₂H₁₉F₃N₄O₂
SMILES

O=C(N1CCC2=C1C=C(C(F)(F)F)C(C)=C2)NC3=CC=C(OCC4=NC=CC=C4)N=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Theis J G, et al. Orthostatic intolerance induced by the 5‐HT2C antagonist SB‐247853 in healthy volunteers during head‐up tilting. Clinical Pharmacology & Therapeutics, 2005, 77(2): P66-P66.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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SB-247853

Voir tous les produits spécifiques à Isoform 5-HT Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

SB-247853 Related Classifications

HY-19297 Related Classifications