Rabep1 - rabaptin, RAB GTPase binding effector protein 1 Gene

Also Known as Rab5ep; rabaptin-5; rabaptin-5alpha

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54189

Summary

Predicted to enable protein domain specific binding activity and protein homodimerization activity. Involved in Golgi to plasma membrane transport and protein localization to ciliary membrane. Located in endosome. Is expressed in brain; embryo; head; lung; and thymus. Orthologous to human RABEP1 (rabaptin, RAB GTPase binding effector protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Rabep1 Products (4)

mRNA Protein Name
NM_001291141.1 NP_001278070.1 rab GTPase-binding effector protein 1 isoform 2
NM_001291142.1 NP_001278071.1 rab GTPase-binding effector protein 1 isoform 3
NM_001291143.1 NP_001278072.1 rab GTPase-binding effector protein 1 isoform 4
NM_019400.3 NP_062273.2 rab GTPase-binding effector protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
17341663 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in Golgi to plasma membrane transport IMP
IMP: Inferred from mutant phenotype
25405894 MGI
involved in protein localization to ciliary membrane IMP
IMP: Inferred from mutant phenotype
25405894 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
34564930 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: Inferred from mutant phenotype
34564930 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in endosome IDA
IDA: Inferred from direct assay
12890772 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
34564930 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
34564930 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rab GTPase-binding effector protein 1

  • RAB5 effector protein

  • neurocrescin

  • rabaptin 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS11582 RABEP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rabep1 NCBI NCBI:9135