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Art. -Nr.: HY-100807S1

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Quinolinic acid-¹³C₇

Quinolinic acid-¹³C₇ is the ¹³C labeled Quinolinic acid (HY-100807). Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis.

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CAS. Nr.: 1346642-91-8
Formel: ¹³C₇H₅NO₄
Molecular Weight:174.07

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (250 KB)

Quinolinic acid-¹³C₇ Chemical Structure

CAS. Nr.: 1346642-91-8

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Biologische Aktivität

Beschreibung

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen :

Alle iGluR Isoform-spezifische Produkte anzeigen :

Alle NO Synthase Isoform-spezifische Produkte anzeigen :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS. Nr. 1346642-91-8
Unlabeled Cas 89-00-9
Molecular Weight 174.07
Formel ¹³C₇H₅NO₄
SMILES

O[13C]([13C]1=[13C](N=[13CH][13CH]=[13CH]1)[13C](O)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.