Cefovecin sodium
Based on 1 Customer Validation
Cefovecin sodium is an extended-spectrum semisynthetic cephalosporin and bactericidal agent. Cefovecin sodium exerts potent antibacterial activity against multiple bacterial. Cefovecin sodium can be used for the research of bacterial infection.
For research use only. We do not sell to patients.
- Purity: 99.79%
- CAS No.: 141195-77-9
- Formula: C17H18N5NaO6S2
- Molecular Weight:475.47
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Antibiotic Isoforms
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Biological Activity
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β-lactam |
Cefovecin sodium (0.06-32 μg/mL; 16-48 h) exhibits broad-spectrum in vitro activity against most aerobic and anaerobic bacterial clinical isolates from dogs and cats associated with skin, urinary tract, and periodontal infections, with MIC90 values as low as ≤0.06 μg/ml (for Pasteurella multocida, U.S. beta-hemolytic streptococci, U.S. Streptococcus canis, and U.S. Porphyromonas spp.) and 0.25 μg/ml (for Staphylococcus intermedius, EU and U.S.), but shows negligible activity against Enterococcus spp. (MIC90 >32 μg/ml) and limited activity against Acinetobacter baumannii[1].
Cefovecin sodium (0.06-32 μg/mL; 16-48 h) exhibits bactericidal activity against most tested aerobic gram-positive and gram-negative bacterial isolates from dogs and cats, with MBC:MIC ratios ≤2 for the majority of isolates, while anaerobic isolates show higher MBC:MIC ratios[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 141195-77-9
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Appearance Solid
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Molecular Weight 475.47
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Formula C17H18N5NaO6S2
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Color White to off-white
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SMILES
O=C(C(N12)=C([C@H]3OCCC3)CS[C@]2([H])[C@H](NC(/C(C4=CSC(N)=N4)=N\OC)=O)C1=O)O[Na]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 125 mg/mL (262.90 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.1032 mL | 10.5159 mL | 21.0318 mL | 52.5796 mL |
| 5 mM | 0.4206 mL | 2.1032 mL | 4.2064 mL | 10.5159 mL | |
| 10 mM | 0.2103 mL | 1.0516 mL | 2.1032 mL | 5.2580 mL | |
| 15 mM | 0.1402 mL | 0.7011 mL | 1.4021 mL | 3.5053 mL | |
| 20 mM | 0.1052 mL | 0.5258 mL | 1.0516 mL | 2.6290 mL | |
| 25 mM | 0.0841 mL | 0.4206 mL | 0.8413 mL | 2.1032 mL | |
| 30 mM | 0.0701 mL | 0.3505 mL | 0.7011 mL | 1.7527 mL | |
| 40 mM | 0.0526 mL | 0.2629 mL | 0.5258 mL | 1.3145 mL | |
| 50 mM | 0.0421 mL | 0.2103 mL | 0.4206 mL | 1.0516 mL | |
| 60 mM | 0.0351 mL | 0.1753 mL | 0.3505 mL | 0.8763 mL | |
| 80 mM | 0.0263 mL | 0.1314 mL | 0.2629 mL | 0.6572 mL | |
| 100 mM | 0.0210 mL | 0.1052 mL | 0.2103 mL | 0.5258 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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