4-Ethylbenzaldehyde
Based on 1 Customer Validation
4-Ethylbenzaldehyde is an aldehyde type organic compound with an almond-like odor. 4-Ethylbenzaldehyde is naturally present in various foods such as grilled meat, black tea, peanuts, etc. 4-Ethylbenzaldehyde has significant effects in controlling plant parasitic nematodes. 4-Ethylbenzaldehyde has genotoxicity and potential for liver damage in zebrafish models.
For research use only. We do not sell to patients.
- Purity: 99.06%
- CAS No.: 4748-78-1
- Formula: C9H10O
- Molecular Weight:134.18
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
4-Ethylbenzaldehyde (0-250 μg/mL, 48 h) completely kills Meloidogyne incognita at a rate of 100% at 250μg/mL with median lethal concentration (LC50) and 95% lethal concentration (LC95) of 33 μg/mL and 88 μg/mL respectively[1].
4-Ethylbenzaldehyde (150 μg/mL, 48 h) reduces the hatching rate of nematode eggs by 99%[1].
4-Ethylbenzaldehyde (1 mL/liter) completely inhibits nematode infection (the number of root knots) and reproduction (the number of eggs)[1].
4-Ethylbenzaldehyde (2.75-11 mg/L) significantly induces micronucleus formation in zebrafish in all concentration groups, and there was no concentration-dependent effect[2].
4-Ethylbenzaldehyde (11 mg/L) causes severe fatty infiltration in the liver of zebrafish[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4748-78-1
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Appearance Liquid (Density: 0.979 g/cm3)
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Molecular Weight 134.18
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Formula C9H10O
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Color Colorless to light yellow
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SMILES
O=CC1=CC=C(CC)C=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 200 mg/mL (1490.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (37.26 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (37.26 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.4527 mL | 37.2634 mL | 74.5268 mL | 186.3169 mL |
| 5 mM | 1.4905 mL | 7.4527 mL | 14.9054 mL | 37.2634 mL | |
| 10 mM | 0.7453 mL | 3.7263 mL | 7.4527 mL | 18.6317 mL | |
| 15 mM | 0.4968 mL | 2.4842 mL | 4.9685 mL | 12.4211 mL | |
| 20 mM | 0.3726 mL | 1.8632 mL | 3.7263 mL | 9.3158 mL | |
| 25 mM | 0.2981 mL | 1.4905 mL | 2.9811 mL | 7.4527 mL | |
| 30 mM | 0.2484 mL | 1.2421 mL | 2.4842 mL | 6.2106 mL | |
| 40 mM | 0.1863 mL | 0.9316 mL | 1.8632 mL | 4.6579 mL | |
| 50 mM | 0.1491 mL | 0.7453 mL | 1.4905 mL | 3.7263 mL | |
| 60 mM | 0.1242 mL | 0.6211 mL | 1.2421 mL | 3.1053 mL | |
| 80 mM | 0.0932 mL | 0.4658 mL | 0.9316 mL | 2.3290 mL | |
| 100 mM | 0.0745 mL | 0.3726 mL | 0.7453 mL | 1.8632 mL |
4-Ethylbenzaldehyde Related Classifications
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