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Cat. No.: HY-160647

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CCR8 antagonist 3

CCR8 antagonist 3 (compound 2) is a CCR8 antagonist with an IC₅₀ value of 0.062 µM. CCR8 antagonist 3 shows human microsomal stability.

For research use only. We do not sell to patients.

CAS No.: 912463-57-1
Formula: C₂₉H₃₃N₃O₄
Molecular Weight:487.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

CCR8 antagonist 3 Chemical Structure

CAS No.: 912463-57-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

CCR8 antagonist 3 (compound 2) is a CCR8 antagonist with an IC₅₀ value of 0.062 µM. CCR8 antagonist 3 shows human microsomal stability^[1].

IC₅₀ & Target^[1]

CCR8

0.062 μM (IC₅₀)

All CCR Isoforms :

Chemical Information

CAS No. 912463-57-1
Molecular Weight 487.59
Formula C₂₉H₃₃N₃O₄
SMILES

COC1=CC=CC=C1OC2=CC=CC=C2CN3CCC4(CCN(C(C5=CC=CNC5=O)=O)CC4)CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Stephen Connolly, et al. Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases. WO2006107254A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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CCR8 antagonist 3

All CCR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CCR8 antagonist 3 Related Classifications

HY-160647 Related Classifications