Sh3pxd2a - SH3 and PX domains 2A Gene

Also Known as Fish; TSK5; Tks5; Gm5098; Sh3md1; EG329070; C230050L11; 2310014D11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14218

Summary

Enables phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and protease binding activity. Involved in Reactive Oxygen Species metabolic process. Acts upstream of or within in utero embryonic development. Located in cytoplasm and podosome. Is expressed in several structures, including brain; clavicle; liver; skeletal muscle; and spleen. Orthologous to human SH3PXD2A (SH3 and PX domains 2A). [provided by Alliance of Genome Resources, Apr 2022]

Sh3pxd2a Products (2)

mRNA Protein Name
NM_001164717.1 NP_001158189.1 SH3 and PX domain-containing protein 2A isoform 2
NM_008018.4 NP_032044.2 SH3 and PX domain-containing protein 2A isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphatidylinositol binding IMP
IMP: Inferred from mutant phenotype
12615925 MGI
enables phosphatidylinositol-3,4-bisphosphate binding IMP
IMP: Inferred from mutant phenotype
12615925 MGI
enables phosphatidylinositol-3-phosphate binding IMP
IMP: Inferred from mutant phenotype
12615925 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IMP
IMP: Inferred from mutant phenotype
12615925 MGI
enables phosphatidylinositol-4-phosphate binding IMP
IMP: Inferred from mutant phenotype
12615925 MGI
enables phosphatidylinositol-5-phosphate binding IMP
IMP: Inferred from mutant phenotype
12615925 MGI
enables protease binding IPI
IPI: Inferred from physical interaction
12615925 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19755709 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
27996060 MGI
involved in reactive oxygen species metabolic process IMP
IMP: Inferred from mutant phenotype
19755709 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12615925 MGI
located in podosome IDA
IDA: Inferred from direct assay
12615925 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SH3 and PX domain-containing protein 2A

  • SH3 multiple domains 1

  • SH3 multiple domains protein 1

  • five SH3 domain-containing protein

  • five SH3 domains

  • tyrosine kinase substrate with five SH3 domains

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12842 SH3PXD2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22070 Sh3pxd2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sh3pxd2a NCBI NCBI:9644