439 Results for "

monocyte

" in MedChemExpress (MCE) Product Catalog:
Products (439)

439 Results for "monocyte" in MCE Product Catalog:

386
386 Publications Verification
Cat. No.: HY-14648
CAS No.: 50-02-2
Purity:  99.86%
Synonyms: Hexadecadrol; Prednisolone F
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist, apoptosis inducer, and common disease inducer in experimental animals, constructing models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has potential for use in COVID-19 research .
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386
386 Publications Verification
Cat. No.: HY-14648C
CAS No.: 50-02-2
Purity:  ≥98.0%
Synonyms: Dexamethasone cyclodextrin complex
Dexamethasone (Hexadecadrol) Water Soluble is a water-soluble form of Dexamethasone (HY-14648). Dexamethasone is a glucocorticoid receptor agonist, apoptosis inducer, and a common disease inducer in experimental animals. It can be used to construct models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has the potential to be used in COVID-19 research .(Sale size is the weight of dexamethasone)
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29
29 Cited Publications
Cat. No.: HY-B0498
CAS No.: 130641-38-2
Synonyms: AF2838
Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity .
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21
21 Cited Publications
Cat. No.: HY-129905
CAS No.: 6491-83-4
Purity:  98.92%
Synonyms: LLOMe hydrochloride; Leu-Leu methyl ester hydrochloride; H-Leu-Leu-OMe hydrochloride
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrochloride, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrochloride also can induce endolysosomal pathway stress .
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21
21 Cited Publications
Cat. No.: HY-129905A
CAS No.: 16689-14-8
Purity:  99.69%
Synonyms: LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress .
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18
18 Cited Publications
Cat. No.: HY-P1846
CAS No.: 219127-21-6
Target:  

Notch

Research Areas:  

Cancer

Jagged-1 (188-204) is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells .
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18
18 Cited Publications
Cat. No.: HY-P1846A
Target:  

Notch

Research Areas:  

Cancer

Jagged-1 (188-204) TFA is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells .
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9
9 Cited Publications
Cat. No.: HY-P7237
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL2; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 2; Prev. SCYA2; Chemokine (C-C Motif) Ligand 2; MCP-1; monocyte Chemotactic Protein 1; MCP1; Small-Inducible Cytokine A2; MCAF; C-C Motif Chemokine 2; HC11; MGC9434; monocyte Chemotactic And Act
Species:  
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9
9 Cited Publications
Cat. No.: HY-P7764
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL2; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 2; Prev. SCYA2; Chemokine (C-C Motif) Ligand 2; MCP-1; monocyte Chemotactic Protein 1; MCP1; Small-Inducible Cytokine A2; MCAF; C-C Motif Chemokine 2; HC11; MGC9434; monocyte Chemotactic And Act
Species:  
Source:  
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7
7 Cited Publications
Cat. No.: HY-N7038
CAS No.: 9008-97-3
Synonyms: PHA-M
Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, is a T-cell activator. Phytohemagglutinin stimulates human mononuclear leukocytes, inducing the expression of ChAT mRNA and potentiating ACh synthesis. Phytohemagglutinin induces dose- and time-dependent toxicity in THP-1 monocytes/macrophages, alters cellular morphology, causes organelle dysfunction, and increases the expression of NF-κB, COX2, IL-1β .
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7
7 Cited Publications
Cat. No.: HY-139414
CAS No.: 9008-30-4
Purity:  ≥99.0%
Lysophosphatidylcholines is an orally active lysolipid and a component of oxidized low density lipoprotein (LDL). Lysophosphatidylcholines induces cell injury, the production of IL-1β and apoptosis. Lysophosphatidylcholines has a proactive effect on sepsis .
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7
7 Cited Publications
Cat. No.: HY-P7224
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; Lung Giant Cell Carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; Neutrophil-Activating Peptide 1; MONAP; T-Cell Chemotactic Factor; GCP-1; Interleukin 8; monocyte-Derived Neutrophil Chemotactic Factor; Interleukin-8; monocyte-Derived Neutrophil-Activating Peptide; Emoctakin; Granulocyte Chemotactic Protein 1; AMCF-I; Chemokine (C-X-C Motif) Ligand 8; B-ENAP; SCYB8; TSG-1; LYNAP; 3-10C; LUCT; K60; LECT; Small Inducible Cytokine Subfamily B, Member 8; IL-8; Beta-Thromboglobulin-Like Protein; GCP1; Neutrophil-Activating Protein 1; NAP1; C-X-C Motif Chemokine 8; NAF; C-X-C Motif Chemokine; Beta Endothelial Cell-Derived Neutrophil Activating Peptide; Protein 3-10C; C-X-C Motif Chemokine Ligand 8; Lymphocyte Derived Neutrophil Activating Peptide
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6
6 Cited Publications
Cat. No.: HY-106634
CAS No.: 459-86-9
Purity:  99.33%
Synonyms: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG
Target:  

HIV Apoptosis

Research Areas:  

Infection Cancer

Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .
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5
5 Cited Publications
Cat. No.: HY-13682
CAS No.: 83461-56-7
Purity:  ≥98.0%
Synonyms: MTP-PE; L-MTP-PE; CGP 19835
Research Areas:  

Inflammation/Immunology Cancer

Mifamurtide (MTP-PE), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide has potential for use in rare disease and osteosarcoma research .
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5
5 Cited Publications
Cat. No.: HY-B0253
CAS No.: 36322-90-4
Synonyms: CP-16171
Target:  

COX

Research Areas:  

Inflammation/Immunology Cancer

Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively.
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5
5 Cited Publications
Cat. No.: HY-13682B
CAS No.: 90825-43-7
Purity:  98.19%
Synonyms: MTP-PE sodium; L-MTP-PE sodium; CGP 19835 sodium
Research Areas:  

Inflammation/Immunology Cancer

Mifamurtide sodium (MTP-PE sodium), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide sodium is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide sodium has potential for use in rare disease and osteosarcoma research .
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5
5 Cited Publications
Cat. No.: HY-13682C
Purity:  ≥98.0%
Synonyms: MTP-PE TFA; L-MTP-PE TFA; CGP 19835 TFA
Research Areas:  

Inflammation/Immunology Cancer

Mifamurtide TFA (MTP-PE TFA), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide TFA is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide TFA has potential for use in rare disease and osteosarcoma research .
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5
5 Cited Publications
Cat. No.: HY-P7243
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL7; monocyte Chemotactic Protein 3; Prev. SCYA6; FIC; Prev. SCYA7; Small Inducible Cytokine A7 (monocyte Chemotactic Protein 3); MCP-3; Chemokine (C-C Motif) Ligand 7; NC28; Small-Inducible Cytokine A7; MCP3; C-C Motif Chemokine 7; monocyte Chemoattract
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5
5 Cited Publications
Cat. No.: HY-121268
CAS No.: 127-33-3
Purity:  ≥98.0%
Target:  

Antibiotic Bacterial

Demeclocycline is an orally active tetracycline antibiotic. Demeclocycline impairs protein synthesis by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA. Demeclocycline shows anti-bacterial activitise to a wide variety of bacterial infections .
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5
5 Cited Publications
Cat. No.: HY-17560
CAS No.: 64-73-3
Demeclocycline hydrochloride is an orally active tetracycline antibiotic that inhibits the binding of aminoacyl tRNA by binding to the 30S ribosomal subunit, thereby affecting protein synthesis. Demeclocycline hydrochloride exhibits antibacterial activity against a broad spectrum of bacterial infections .
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