130641-38-2
130641-38-2
Chemical Structure
Bindarit
Synonym(s): AF2838
- CAS No.: 130641-38-2
- Formula:C19H20N2O3
- Molecular Weight:324.37
IUPAC Name: 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid
InChIKey: MTHORRSSURHQPZ-UHFFFAOYSA-N
SMILES: CC(OCC1=NN(CC2=CC=CC=C2)C3=C1C=CC=C3)(C)C(O)=O
Biological Activity: Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bindarit | 99.51% | Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity. | ||||||||||||||||||||
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AF-2785 | AF-2785 is a potent CFTR blocker. AF-2785 inhibits the cAMP-activated chloride current in rat epididymal cells with an IC50 of 170.6 μM. AF-2785 can be used in research related to contraceptives. | |||||||||||||||||||||
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Tolnidamine | Tolnidamine is an orally active sperm production inhibitor. | |||||||||||||||||||||
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Demethyl Benzydamine-d3 hydrochloride | Demethyl Benzydamine-d3 (hydrochloride) is the deuterium labeled Demethyl Benzydamine hydrochloride. | |||||||||||||||||||||
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ADB-BINACA | ADB-BINACA is categorized as a synthetic cannabinoid. | |||||||||||||||||||||
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Bendazac (Standard) | ≥98% | Bendazac (Standard) is the analytical standard of Bendazac. This product is intended for research and analytical applications. Bendazac is an oxyacetic acid with anti-inflammatory, antinecrotic, choleretic and antilipidaemic properties. Bendazac acts by preventing protein denaturation and delays the cataractogenic process. Bendazac exerts funciton in anti-radical effect and inhibits oxidative brust. | ||||||||||||||||||||
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Benzydamine | Benzydamine is an orally administered prostaglandin synthesis inhibitor that has anti-inflammatory, analgesic, antipyretic, and antibacterial properties. Benzydamine can inhibit TNF-α, stabilize cell membranes, and reduce oxidative stress within cells. | |||||||||||||||||||||
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Benzydamine hydrochloride | 99.21% | Benzydamine hydrochloride is an orally administered prostaglandin synthesis inhibitor that has anti-inflammatory, analgesic, antipyretic, and antibacterial properties. Benzydamine hydrochloride can inhibit TNF-α, stabilize cell membranes, and reduce oxidative stress within cells. | ||||||||||||||||||||
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Lonidamine | 99.91% | Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki: 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis. | ||||||||||||||||||||
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Benzydamine N-Oxide | 98.90% | Benzydamine N-Oxide is a metabolite of Benzydamine. Benzydamine N-Oxide can be used to measure flavin-containing monooxygenase activity. | ||||||||||||||||||||
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1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid | 99.90% | 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid is a MRGPRX4 antagonist (IC50: >2.5 μM). | ||||||||||||||||||||
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