130641-38-2
130641-38-2
Chemical Structure
Bindarit
Synonym(s): AF2838
- CAS 番号: 130641-38-2
- Formula:C19H20N2O3
- Molecular Weight:324.37
IUPAC Name: 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid
InChIKey: MTHORRSSURHQPZ-UHFFFAOYSA-N
SMILES: CC(OCC1=NN(CC2=CC=CC=C2)C3=C1C=CC=C3)(C)C(O)=O
Biological Activity: Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity[1].
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Bindarit | 99.51% | Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity. | ||||||||||||||||||||
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