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Referencia número: HY-126311

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4-Hydroxyresveratrol

(Synonyms: 3,4,5,4'-Tetrahydroxystibene)

4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene), a Resveratrol (HY-16561) analog, differentially induces pro-apoptotic p53/Bax gene expression. 4-Hydroxyresveratrol induces apoptosis in SV40 virally transformed WI38 cells (WI38VA) cells, but not in WI38 cells. 4-Hydroxyresveratrol significantly induces the expression of p53, GADD45 and Bax genes and concomitantly suppresses the expression of bcl-2 gene in WI38VA.

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No. CAS: 331443-00-6
Fòrmula: C₁₄H₁₂O₄
Peso molecular:244.24

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

4-Hydroxyresveratrol Chemical Structure

No. CAS: 331443-00-6

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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IC₅₀ & Target^[1]

Bax

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Chemical Information

No. CAS 331443-00-6
Peso molecular 244.24
Fòrmula C₁₄H₁₂O₄
SMILES

OC1=CC(/C=C/C2=CC=C(O)C=C2)=CC(O)=C1O
Synonyms

3,4,5,4'-Tetrahydroxystibene
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. J Lu, et al. Resveratrol analog, 3,4,5,4'-tetrahydroxystilbene, differentially induces pro-apoptotic p53/Bax gene expression and inhibits the growth of transformed cells but not their normal counterparts. Carcinogenesis. 2001 Feb;22(2):321-8. [Content Brief]

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4-Hydroxyresveratrol

Ver todos los productos específicos de isoformas Bcl-2 Family

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4-Hydroxyresveratrol Related Classifications

HY-126311 Related Classifications