B26 peptoid
B26 peptoid is a ptoid antibiotic. B26 peptoid exhibits excellent broad-spectrum activity and high selectivity toward a panel of Gram-positive and Gram-negative bacterial strains. B26 peptoid disrupts bacterial membranes and has bactericidal activity. B26 peptoid shows low propensity for bacterial drug resistance. B26 peptoid can be used for the research of bacterial infection.
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- Fòrmula: C58H114N12O8
- Peso molecular:1107.60
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
B26 peptoid (16 h) potently inhibits the growth of vancomycin-resistant E. faecalis, methicillin-resistant S. aureus, methicillin-resistant S. epidermidis, E. coli, P. aeruginosa, and K. pneumoniae with MIC values ranging from <3 μg/mL[1].
B26 peptoid (2× MIC; 2 h) disrupts the cell membranes of methicillin-resistant S. aureus and E. coli, allowing propidium iodide to enter and stain bacterial cells[1].
B26 peptoid (2× MIC; 2 h) causes severe membrane disruption and cellular damage in methicillin-resistant S. aureus and E. coli, as visualized by transmission electron microscopy[1].
B26 peptoid maintains stable, consistent antimicrobial activity against methicillin-resistant S. aureus over 14 serial passages, with no significant development of bacterial drug resistance[1].
B26 peptoid (12 μg/mL; 0-2 h) rapidly kills methicillin-resistant S. aureus and E. coli[1].
B26 peptoid (1 h) has low hemolytic toxicity toward human red blood cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:methicillin-resistant S. aureus; E. col
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Concentration:12 μg/mL
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Incubation Time:0-2 h
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Result:Killed methicillin-resistant S. aureus within 2 hours and E. coli within 1 hour.
Chemical Information
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Peso molecular 1107.60
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Fòrmula C58H114N12O8
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)