UA2239
UA2239 is an antimalarial agent and acyclic nucleoside phosphonate. UA2239 disrupts the essential cGMP-dependent egress pathway by decreasing cGMP levels. UA2239 targets guanylyl cyclase α. UA2239 demonstrates rapid and irreversible inhibitory effects on Plasmodium parasites.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2455422-89-4
- Fòrmula: C9H12N5Na2O5P
- Peso molecular:347.18
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas Parasite
More
Actividad biológica
|
Plasmodium |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
1000 μM
Compound: (R)-5
|
Toxicity in human K562 cells assessed as effect on cell growth measured after 24 hrs by [3H]thymidine incorporation based assay
Toxicity in human K562 cells assessed as effect on cell growth measured after 24 hrs by [3H]thymidine incorporation based assay
|
[PMID: 32687714] |
Chemical Information
-
No. CAS 2455422-89-4
-
Peso molecular 347.18
-
Fòrmula C9H12N5Na2O5P
-
SMILES
O=C1NC(N)=NC2=C1N=CN2CC[C@H](CP(O[Na])(O[Na])=O)O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UA2239 Related Classifications
HY-179656 Related Classifications
Powered by Bioz