Mir31 - microRNA 31 Gene | MedChemExpress

ADC Targets in Oncology

2026-04-10

Mir31 - microRNA 31 Gene

Also Known as Mir31a; rno-mir-31; rno-mir-31a

Species: Rattus norvegicus

Gene Type: ncRNA

Gene ID: 100314232

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	References	Source
involved in negative regulation of epithelial to mesenchymal transition	IMP IMP: Inferred from mutant phenotype	23270756	RGD
involved in positive regulation of mesenchymal cell proliferation	IMP IMP: Inferred from mutant phenotype	23270756	RGD
involved in response to zinc ion	IEP IEP: Inferred from expression pattern	32123074	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Pre-clinical Phase

Cat. No.	Product Name	Purity	Rare Diseases
HY-R00613	hsa-miR-31-5p mimic	96.0%	Unkown
HY-R00580	hsa-miR-31-3p mimic	92.32%	Unkown
HY-RI00613A	hsa-miR-31-5p antagomir	97.44%	Unkown
HY-RI00580	hsa-miR-31-3p inhibitor	93.84%	Unkown
HY-R03017	mmu-miR-31-5p mimic	93.50%	Unkown
HY-RI03017	mmu-miR-31-5p inhibitor	91.15%	Unkown
HY-R00580A	hsa-miR-31-3p agomir	/	Unkown
HY-R00613A	hsa-miR-31-5p agomir	/	Unkown
HY-R03015	mmu-miR-31-3p mimic	/	Unkown
HY-R03015A	mmu-miR-31-3p agomir	/	Unkown
HY-R03017A	mmu-miR-31-5p agomir	/	Unkown
HY-R04346	rno-miR-31b mimic	/	Unkown
HY-R04346A	rno-miR-31b agomir	/	Unkown
HY-RI00580A	hsa-miR-31-3p antagomir	/	Unkown
HY-RI00613	hsa-miR-31-5p inhibitor	/	Unkown
HY-RI03015	mmu-miR-31-3p inhibitor	/	Unkown
HY-RI03015A	mmu-miR-31-3p antagomir	/	Unkown
HY-RI03017A	mmu-miR-31-5p antagomir	/	Unkown
HY-RI04346	rno-miR-31b inhibitor	/	Unkown
HY-RI04346A	rno-miR-31b antagomir	/	Unkown

Cat. No.

Product Name

Effect