2. Gene
  3. Mir31 - microRNA 31 Gene

Mir31 - microRNA 31 Gene

  • Gene
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mir31a; rno-mir-31; rno-mir-31a

Gene ID: 100314232 | Gene type: ncRNA

About Mir31

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
23270756 RGD
involved in positive regulation of mesenchymal cell proliferation IMP
IMP: Inferred from mutant phenotype
23270756 RGD
involved in response to zinc ion IEP
IEP: Inferred from expression pattern
32123074 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (20)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-R00613 hsa-miR-31-5p mimic 96.0% Unkown
HY-R00580 hsa-miR-31-3p mimic 92.32% Unkown
HY-RI00613A hsa-miR-31-5p antagomir 97.44% Unkown
HY-RI00580 hsa-miR-31-3p inhibitor 93.84% Unkown
HY-R03017 mmu-miR-31-5p mimic 93.50% Unkown
HY-RI03017 mmu-miR-31-5p inhibitor 91.15% Unkown
HY-R00580A hsa-miR-31-3p agomir / Unkown
HY-R00613A hsa-miR-31-5p agomir / Unkown
HY-R03015 mmu-miR-31-3p mimic / Unkown
HY-R03015A mmu-miR-31-3p agomir / Unkown
HY-R03017A mmu-miR-31-5p agomir / Unkown
HY-R04346 rno-miR-31b mimic / Unkown
HY-R04346A rno-miR-31b agomir / Unkown
HY-RI00580A hsa-miR-31-3p antagomir / Unkown
HY-RI00613 hsa-miR-31-5p inhibitor / Unkown
HY-RI03015 mmu-miR-31-3p inhibitor / Unkown
HY-RI03015A mmu-miR-31-3p antagomir / Unkown
HY-RI03017A mmu-miR-31-5p antagomir / Unkown
HY-RI04346 rno-miR-31b inhibitor / Unkown
HY-RI04346A rno-miR-31b antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir31 NCBI NCBI:407035