Nuggc - nuclear GTPase, germinal center associated Gene

Also Known as Gm600; SLIP-GC

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100503545

Summary

Predicted to enable GTPase activity. Acts upstream of or within cellular response to DNA damage stimulus and somatic hypermutation of immunoglobulin genes. Located in nucleus. Orthologous to human NUGGC (nuclear GTPase, germinal center associated). [provided by Alliance of Genome Resources, Apr 2022]

Nuggc Products (1)

mRNA Protein Name
NM_001195674.2 NP_001182603.2 nuclear GTPase SLIP-GC

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA damage response IMP
IMP: Inferred from mutant phenotype
22833677 MGI
acts upstream of or within somatic hypermutation of immunoglobulin genes IMP
IMP: Inferred from mutant phenotype
22833677 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
22833677 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear GTPase SLIP-GC

  • speckled-like pattern in the germinal center

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09679 NUGGC Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nuggc NCBI NCBI:389643