NUGGC - nuclear GTPase, germinal center associated Gene

Homo sapiens

Also known as SLIPGC; C8orf80; SLIP-GC; HMFN0672

Gene ID: 389643 | Gene type: protein coding

About NUGGC

Cytogenetic location: 8p21.1 Genomic coordinates (GRCh38): 8:28,021,964-28,083,936 (from NCBI)

This gene has 2 transcripts (splice variants) and 216 orthologues. Biased expression in lymph node (RPKM 5.9), liver (RPKM 3.6) and 9 other tissues.

Summary

Enables GTPase activity. Involved in cellular response to lipopolysaccharide; negative regulation of apoptotic process; and regulation of nuclear cell cycle DNA replication. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NUGGC Products(1)

mRNA	Protein	Name
NM_001010906.2	NP_001010906.1	nuclear GTPase SLIP-GC

NUGGC Protein Structure

Dynamin_N

0
200
400
600
796 a.a.

Protein Preferred Names

Protein Names

nuclear GTPase SLIP-GC

GTPase SLIP-GC

Related Diseases

Diseases

Alias

Endometrial Stromal Sarcoma

Ess	Endometrial Stromal Sarcoma, High Grade
Undifferentiated Endometrial Sarcoma	Stromal Sarcoma Of The Corpus Uteri
Sarcoma Endometrial Stromal	Sarcoma, Endometrial Stromal
Undifferentiated Stromal Sarcoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09679	NUGGC Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	NUGGC	VGNC	VGNC:32347
Rattus norvegicus	NUGGC	RGD	RGD:1562099
Felis catus	NUGGC	VGNC	VGNC:63917
Canis familiaris	NUGGC	VGNC	VGNC:44041
Mus musculus	NUGGC	MGD	MGI:2685446
Macaca mulatta	NUGGC	VGNC	VGNC:75497

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