Gbp6 - guanylate binding protein 6 Gene

Also Known as GBP-6; Mpa2l

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100702

Summary

Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within several processes, including cellular response to interferon-beta; cellular response to lipopolysaccharide; and defense response to Other organism. Located in cytoplasmic vesicle and symbiont-containing vacuole membrane. Is expressed in several structures, including alimentary system; dorsal root ganglion; nasal cavity epithelium; vertebral axis musculature; and vibrissa. Orthologous to human GBP6 (guanylate binding protein family member 6). [provided by Alliance of Genome Resources, Apr 2022]

Gbp6 Products (1)

mRNA Protein Name
NM_194336.2 NP_919317.2 guanylate-binding protein 6

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within adhesion of symbiont to host IDA
IDA: Inferred from direct assay
18025219 MGI
acts upstream of or within cellular response to interferon-beta IDA
IDA: Inferred from direct assay
19158679 MGI
involved in cellular response to interferon-beta IDA
IDA: Inferred from direct assay
18025219 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
18025219 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: Inferred from direct assay
18025219 MGI
acts upstream of or within defense response to Gram-positive bacterium IDA
IDA: Inferred from direct assay
18025219 MGI
acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
21551061 MGI
acts upstream of or within defense response to protozoan IDA
IDA: Inferred from direct assay
18025219 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
18025219 MGI
located in symbiont-containing vacuole membrane IDA
IDA: Inferred from direct assay
18025219 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanylate-binding protein 6

guanylate binding protein 6

  • GTP-binding protein 6

  • guanine nucleotide-binding protein 6

  • macrophage activation 2 like

  • macrophage activation 2 like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05312 GBP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22181 Gbp6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28703 Gbp6 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gbp6 NCBI NCBI:163351