IDH2 - isocitrate dehydrogenase (NADP(+)) 2 Gene

Also Known as IDH; IDP; ICD-M

Species: Macaca fascicularis

Gene Type: protein coding
Gene ID: 101925784

About IDH2

Primary_assembly 7: 68,692,582-68,718,514 reverse strand.Macaca_fascicularis_6.0:CM021945.1

This gene has 2 transcripts (splice variants), 261 orthologues and 1 paralogue.

IDH2 Products (4)

mRNA Protein Name
XM_045395995.1 XP_045251930.1 isocitrate dehydrogenase [NADP], mitochondrial isoform X1
XM_015453247.2 XP_015308733.1 isocitrate dehydrogenase [NADP], mitochondrial isoform X2
XM_015453247.2 XP_015308733.1 isocitrate dehydrogenase [NADP], mitochondrial isoform X2
XM_045395995.1 XP_045251930.1 isocitrate dehydrogenase [NADP], mitochondrial isoform X1

IDH2 Protein Structure

Iso_dh

Iso_dh: cl00445 (0 - 320)

  • 0
  • 100
  • 200
  • 300
  • 322 a.a.
Protein Preferred Names Protein Names

isocitrate dehydrogenase [NADP], mitochondrial

  • Isocitrate dehydrogenase [NADP], mitochondrial

  • NADP(+)-specific ICDH

  • Oxalosuccinate decarboxylase

  • isocitrate dehydrogenase (NADP(+)) 2, mitochondrial

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-104042 Vorasidenib Inhibitor 99.76% Yes
HY-18690 Enasidenib Inhibitor 99.93% Yes
HY-18690A Enasidenib mesylate Inhibitor 99.68% Yes

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-131312 Crelosidenib Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15734 AGI-6780 Inhibitor 99.26% Unkown
HY-164542 TQ05310 Inhibitor / Unkown
HY-149359 IHMT-IDH1-053 Inhibitor / Unkown
HY-145743 CP-17 Inhibitor / Unkown
HY-120765 BRD2879 Inhibitor / Unkown
HY-131312A Crelosidenib gentisate Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens IDH2 NCBI NCBI:3418