LRRC23 - leucine rich repeat containing 23 Gene

Also Known as LRPB7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10233

About LRRC23

This gene has 15 transcripts (splice variants), 185 orthologues and 13 paralogues. Broad expression in testis (RPKM 16.2), lung (RPKM 5.4) and 20 other tissues.

Summary

Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

LRRC23 Products (3)

mRNA Protein Name
NM_001135217.2 NP_001128689.1 leucine-rich repeat-containing protein 23 isoform a
NM_006992.4 NP_008923.1 leucine-rich repeat-containing protein 23 isoform b
NM_201650.3 NP_964013.1 leucine-rich repeat-containing protein 23 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
37804054 GOA
involved in radial spoke assembly IMP
IMP: Inferred from mutant phenotype
37804054 GOA
Cellular Component GO Annotation Evidence References Source
located in sperm flagellum IMP
IMP: Inferred from mutant phenotype
37804054 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LRRC23 Protein Structure

LRR_1

LRR_1: Leucine Rich Repeat (92 - 109)

LRR_9

LRR_9: Leucine-rich repeat (185 - 317)

  • 0
  • 100
  • 200
  • 300
  • 343 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat-containing protein 23

  • leucine-rich protein B7

LRRC23 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
LRRC23 Q53EV4 CEP55 Homo sapiens Q53EZ4
Validated Y2H
32296183
Intra
LRRC23 Q53EV4 CEP55 Homo sapiens Q53EZ4
Y2H Prey Pooling
32296183
Intra
LRRC23 Q53EV4 CEP55 Homo sapiens Q53EZ4
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Renal Wilms' Tumor

  • Nonanaplastic Renal Wilm'S Tumor

  • Nonanaplastic Renal Wilm'S Tumour

  • Nonanaplastic Renal Wilms Tumor

  • Renal Wilms' Tumour
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07811 LRRC23 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris LRRC23 VGNC VGNC:57433
Mus musculus LRRC23 MGD MGI:1315192
Macaca mulatta LRRC23 VGNC VGNC:100074
Bos taurus LRRC23 VGNC VGNC:56220
Rattus norvegicus LRRC23 RGD RGD:1304779
Others LRRC23 NCBI