PRG3 - proteoglycan 3, pro eosinophil major basic protein 2 Gene

Homo sapiens

Also known as MBP2; MBPH

Gene ID: 10394 | Gene type: protein coding

About PRG3

Cytogenetic location: 11q12.1 Genomic coordinates (GRCh38): 11:57,376,769-57,381,150 (from NCBI)

This gene has 1 transcript (splice variant), 110 orthologues and 1 paralogue. Restricted expression toward bone marrow (RPKM 15.2).

Summary

An extracellular matrix structural constituent conferring compression resistance. Involved in several processes, including granulocyte activation; histamine biosynthetic process; and regulation of gene expression. Located in collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

PRG3 Products(1)

mRNA	Protein	Name
NM_006093.4	NP_006084.2	proteoglycan 3 precursor

PRG3 Protein Structure

Lectin_C

0
100
200
225 a.a.

Protein Preferred Names

Protein Names

proteoglycan 3

eosinophil major basic protein homolog

Recombinant PRG3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71233	PRG3 Protein, Human (HEK293, His)	AAI13412.1 (L18-F225)	≥95%

Related Diseases

Diseases

Alias

Oropouche Fever

Oropouche Virus Disease

Oropouche Mosquito-Borne Viral Fever

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11089	PRG3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PRG3	RGD	RGD:1309904
Felis catus	PRG3	VGNC	VGNC:104346
Mus musculus	PRG3	MGD	MGI:1858200
Macaca mulatta	PRG3	VGNC	VGNC:76397
Canis familiaris	PRG3	VGNC	VGNC:52036
Others	PRG3	NCBI