1. Gene
  2. BASP1 - brain abundant membrane attached signal protein 1 Gene

BASP1 - brain abundant membrane attached signal protein 1 Gene

Homo sapiens

Also known as CAP23; NAP22; CAP-23; NAP-22

Gene ID: 10409 | Gene type: protein coding

About BASP1

Cytogenetic location: 5p15.1 Genomic coordinates (GRCh38): 5:17,216,823-17,276,834 (from NCBI)

This gene has 3 transcripts (splice variants) and 110 orthologues. Biased expression in brain (RPKM 144.2), prostate (RPKM 45.3) and 10 other tissues.

Summary

This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2012]

BASP1 Products(2)

mRNA Protein Name
NM_001271606.2 NP_001258535.1 brain acid soluble protein 1
NM_006317.5 NP_006308.3 brain acid soluble protein 1

BASP1 Protein Structure

BASP1

BASP1: Brain acid soluble protein 1 (BASP1 protein) (2 - 227)

  • 0
  • 100
  • 200
  • 227 a.a.
Protein Preferred Names Protein Names

brain acid soluble protein 1

22 kDa neuronal tissue-enriched acidic protein

Related Diseases

Diseases Alias
Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta BASP1 VGNC VGNC:70228
Bos taurus BASP1 VGNC VGNC:106649
Rattus norvegicus BASP1 RGD RGD:621491
Mus musculus BASP1 MGD MGI:1917600
Canis familiaris BASP1 VGNC VGNC:38384