Barhl2 - BarH like homeobox 2 Gene

Also Known as MBH1; E130309B19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 104382

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Acts upstream of or within several processes, including generation of neurons; positive regulation of macromolecule biosynthetic process; and regulation of axon extension. Located in nucleus. Is expressed in several structures, including alimentary system epithelium; eye; and nervous system. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human BARHL2 (BarH like homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Barhl2 Products (1)

mRNA Protein Name
NM_001005477.1 NP_001005477.1 barH-like 2 homeobox protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
18212062 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within amacrine cell differentiation IDA
IDA: Inferred from direct assay
14998930 MGI
acts upstream of or within cell fate commitment IDA
IDA: Inferred from direct assay
14998930 MGI
acts upstream of or within cell fate determination IMP
IMP: Inferred from mutant phenotype
12657654 MGI
acts upstream of or within neuron differentiation IMP
IMP: Inferred from mutant phenotype
12657654 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
12657654 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18212062 MGI
acts upstream of or within positive regulation of translation IMP
IMP: Inferred from mutant phenotype
12657654 MGI
acts upstream of or within regulation of axon extension IMP
IMP: Inferred from mutant phenotype
12657654 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
14998930 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

barH-like 2 homeobox protein

  • BarH-class homeodomain transcription factor

  • bar-class homeodomain protein MBH1

  • homeobox protein B-H1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01367 BARHL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Barhl2 NCBI NCBI:343472